With an established pedigree in Neuroscience, Biotrial provides translational solutions that closely link non-clinical and clinical development using in-house data validation and back translation. Biotrial’s excellence is driven by our team of in house and external neurologists’ experts as well as project management teams with significant expertise in Neuroscience trials. We offer an end-to-end solution for your Early Phase needs or bespoke services according to your needs.
Extensive early development expertise in Phase I and II worldwide:
Drug development programs support by developing and validating bioanalytical LC-MS/MS methods and performing high-throughput analysis for accurate quantification of drugs, from matrices such as blood, plasma, cerebrospinal fluid, and brain tissue.
Neurodegenerative disorders
Alzheimer’s disease, Dementia, Parkinson’s disease, Multiple Sclerosis, Huntington’s disease, Osteoporosis, Rheumatoid Arthritis
Neuromuscular disorders
Amyotrophic Lateral Sclerosis (ALS), Duchenne Muscular Dystrophy (DMD)
Neurodevelopmental disorders
Angelman Syndrome, Fabry Disease
Psychiatry
Depression, Schizophrenia, Anxiety, Panic disorder
PNS disorder
Peripheral neuropathy, radiculopathy
Pain
Back pain, Migraine pain, Neuropathic pain
Vascular Injury
Acute Ischemic Stroke, Diabetic Neuropathy, Peripheral Neuropathy
Sleep disorders
Narcolepsy, Insomnia
Epilepsy
Our Clinical Pharmacology Scientific Services are numerous given our focus on Early Clinical Development and
Translational research. Different pharmacodynamic tests and models are available related to assessment of CNS effects,including ones that are relevant to pain, cognition and psychiatric disorders..
Both our clinics in France and in the US include dedicated CNS-testing areas where study participants can take these tests within a quiet and adapted environment.
EEG, ERP, PSG, Cognitive testing
Imaging (PET, MRI, CT, Sonography)
Wet: Ceresbrospinal Fluid (CSF) sampling
