Biotrial Core Lab provides a CNS testing battery to clinical sites, adapted to the trial needs.
Biotrial’s test battery encompasses various components that facilitate the measurement of:
Our tools are designed to be flexible and can seamlessly integrate sponsor-specific tests & questionnaires.
The CNS tests used by Biotrial enable the sponsors to gather pertinent Pharmacodynamic (PD) data. Often these data complete the clinical observations made by site staff and provide deeper insight into drug effects.
PEPSY Services
PEPSY Software Features
Using a dedicated platform, we implement posturography which is an objective, sensitive, reliable and non-invasive method designed to assess the effects of drugs on body sway and vigilance.
This can be particularly beneficial in trials where an effect is anticipated on these elements, or in alcohol interaction studies where it provides a highly robust endpoint.
Various methods can be set up to measure oculography endpoints which can include:
Different devices, adapted to the requirements indicated for each endpoint, can be used.
For eye-tracking endpoints, where we look to identify which areas of interest are observed by the participant, simple eye-trackers with sampling frequencies of 60-80Hz can be used, however when investigating SEM, Pursuit or Nystagmus, high-frequency sampling is required, and adapted hardware must be used.
Simple Reaction Time (SRT)
Choice Reaction time (CRT)
Tracking test (TT)
Rapid Visual Information Processing (RVIP)
Digit Vigilance (DV)
Divided Attention (DA)
Body Sway (BS)
Saccadic Eye Movement (SEM)
Learning memory task (LMT)
Numeric Working Memory (NWM)
Spatial Working Memory (SWM)
