Our Fit-for-Purpose assays involve a series of tests to obtain optimal conditions for required concentrations and sensitivity.
Prior to sample injection into the LCMS system, we perform a series of quality control checks on the samples. This includes analyzing the samples against a calibration curve and using quality control samples. To extract the samples from their respective matrices, we employ various techniques such as liquid-liquid extraction, solid phase extraction, protein precipitation, or a combination of these techniques that have been developed by our team.
This process separates the analyte(s) of interest from endogenous interferences and/or metabolites. Our scientists are at the chromatographic process forefront and have all the available resources for optimal method development.
Modern liquid chromatography-tandem mass spectrometry (LC-MS/MS) with development of multiple reaction monitoring (MRM) mode for accurate, high-quality and simultaneous multi-analyte quantification.
